ASTRONAM

Description: Astronam Injection is available in dry powder injection.

Dosage:  it is administered intravenous or by intramuscular injection 

Adults –

• Urinary Tract Infection – 500mg or 1gm is slowly administered dilution with normal saline on 8 to 12 hours interval.
• Moderately sever Systemic infection – 1g or 2g slowly administered on dilution with normal saline on 8 to 12 hours interval
• Severe Systemic or Life threating infection – 2g slowly administered on dilution with normal saline on 6 to 8 hours interval Maximum recommended dose is 8g per day

Child –

• Mild to Moderate infection – 30mg/kg, frequently on 8 hours
• Maximum recommended dose for child is 120mg/kg/day

Uses – Aztreonam injection is used for the treatment, control and prevention and improvement of the following disease conditions and symptoms;

• Patients unable to tolerate Penicillin and Cephalosporin
• Pneumonia
• Hospital acquired pneumonia
• Meningitis
• Gram –ve sepsis
• Urinary Tract Infection
• Osteomyelitis

Contraindications – Known hypersensitivity to Aztreonam

Special precautions – May Cause Bronchospasm

Adverse Drug Reactions – Nausea or vomiting that doesn’t stop, fast/irregular heartbeat, Confusion,Easy bruising/bleeding, ringing in the ears, seizures, chest pain, yellowing  Eyes or skin, dark urine, severe stomach/abdominal pain, unusual fatigue

Drug Interactions: BCG Vaccine live, Cholera Vaccine, Typhoid Vaccine live

Mechanism of Action – Aztreonam is a Bactericidal antibiotic which inhibits synthesis of the   bacterial cell wall, by blocking peptidoglycan crosslinking

Presentation – Astronam is Available in pack of 1gm Injection